Yes, GDB has support to conditional breakpoint, then you can get a function fired only when it has right criteria.
In this example I want a breakpoint issued only when my file descriptor (parameter save at r0) is equal to 12:
(gdb) br write if $r0==12 Ponto de parada 2 at 0xab50
In theory it should accept even more elaborated implementations like this:
(gdb) br open64 if strcmp(*((char**)($r0)),"/dev/ttyS1")==0 Ponto de parada 1 at 0xb144
But it didn’t work for me. I also tried replacing by:
(gdb) br open64 if strcmp(*($r0),"/dev/ttyS1")==0
No way, didn’t work either.
I got the idea from this site: http://whats.all.this.brouhaha.com/2007/10/21/reverse-engineering-a-binary-only-linux-library-and-executable/